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A 46-year-old woman of Black African family origin sees her GP after a raised reading at a pharmacy health check. Her clinic blood pressure is 162/102 mmHg, and ambulatory monitoring shows a daytime average of 156/98 mmHg. She does not have diabetes.

Which is the most appropriate first-line antihypertensive drug?

One Case, Four Steps

The same question, taken apart.

  1. 1Read The Stem

    Who
    46-year-old woman
    Family Origin
    Black African
    Blood Pressure
    156/98 mmHg, daytime average
    Diabetes
    None
  2. 2Spot The Clue

    A 46-year-old woman of Black African family origin sees her GP after a raised reading at a pharmacy health check. Her clinic blood pressure is 162/102 mmHg, and ambulatory monitoring shows a daytime average of 156/98 mmHg. She does not have diabetes.

  3. 3Choose

    AmlodipineCorrect

    A calcium-channel blocker is step 1 for adults of Black African or African-Caribbean family origin without type 2 diabetes, at any age.

  4. 4Learn Why

    Black African family origin, no type 2 diabetes

    Type 2 diabetes, any age or origin
    ACE inhibitor or ARB
    Under 55, not Black African or African-Caribbean
    ACE inhibitor or ARB
    55 or over, or Black African or African-Caribbean
    Calcium-channel blocker

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Heart and vasculature1 / 10

A 46-year-old woman of Black African family origin sees her GP after a raised reading at a pharmacy health check. Her clinic blood pressure is 162/102 mmHg, and ambulatory monitoring shows a daytime average of 156/98 mmHg. She does not have diabetes. Her eGFR, urine albumin:creatinine ratio, ECG and fundoscopy are normal. She has already cut down on salt and alcohol.

Which is the most appropriate first-line antihypertensive drug?

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